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Academic Year |
2011
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Course Code |
CHEM2410
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Title |
Analytical techniques for pharmacy students
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Credit |
6
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Department |
Chemistry |
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Course Co-ordinator |
Dr W T Chan, Chemistry
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Teachers Involved |
Dr W T Chan (66.7%); Dr I K Chu (33.3%)
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Course Aim
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This course is designed for Bachelor of Pharmacy students to provide an overview of different analytical and measurement techniques that are important to pharmacology and pharmaceutical sciences.
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Course Contents |
Principles and Applications of different analytical and measurement techniques in pharmaceutical sciences such as drug analysis and pharmacokinetics studies
Analysis and quality assurance: statistical analysis of data, control chart.
Analysis by Optical methods: Beer's Law; instrumentation, grating spectrometer, detectors; absorption spectrometry: UV-visible, infrared, and atomic; emission spectrometry;
Sample Separation and Purification: partition; chromatography theories; high performance liquid chromatography (HPLC) and gas chromatography (GC); instrumentation of HPLC and GC.
Molecular Mass Measurements: mass spectrometry-fundamental concepts; various ionization techniques including electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI); time-of-flight (TOF) and quadrupole (Q) mass analyzers; use of mass spectrometry in drug analysis
Nuclear magnetic resonance: basic principles; instrumentations; applications in structure determination of molecules of biological and pharmaceutical importance
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Learning Outcomes |
On completion of the course, the students should be able to:
- Demonstrate knowledge and understanding of the principles of different optical methods, separation methods, mass spectrometry, NMR spectroscopy and their applications in pharmaceutical sciences
- Describe the basic experimental set up and the properties of the basic components of the instruments used in the laboratory classes.
- Apply experimental skills in chemical analysis including sample preparation, standard solution preparation, instrument calibration, matrix effects correction (standard additions).
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Pre-requisites |
Pass in CHEM1410
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Offer in academic year
2011 - 2012
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2nd sem
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Availability in 2012 - 2013
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Y
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| Examination |
May
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| Teaching Hours |
24 lectures and 7 x 4-hour laboratory sessions
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Assessment Method |
One 2-hour written examination (75% weighting) and course work assessment (25% weighting)
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Quota |
40
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Textbooks |
D.A. Skoog, F.K. Holler, S.R. Crouch: Principles of Instrumental Analysis (Thomson, latest edition).
D.A. Skoog, D.M. West, F.J. Holler, and S.R. Crouch: Fundamentals of Analytical Chemistry (Thomson, latest edition).
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References |
NIL
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Course Website |
NIL
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Remarks |
NIL
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Status |
You had submitted at Feb 10, 2011
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Comment (For Department
Reference Only) |
This course is for pharmacy studentsonly. This course is equivalent to CHEM2003.
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Last updated by CHEM at Feb 10, 2011
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