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Academic Year |
2011
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Course Code |
CHEM3407
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Title |
Medicinal chemistry
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Credit |
6
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Department |
Chemistry |
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Course Co-ordinator |
Prof H Z Sun, Chemistry
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Teachers Involved |
Prof M C Lin (33%), Prof H Z Sun (34%); Guest Lecturer (33%)
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Course Aim
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This course covers the chemical principles of drug design and drug action and uses as an introduction to research in areas of bioorganic chemistry, bioinorganic chemistry, medicinal chemistry, pharmaceutical chemistry, and biotechnology.
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Course Contents |
- Drug discovery, design, and development: lead discovery, pharmacophore, structure-activity relationships (SAR), computer-aided drug design, combinatorial chemistry and high-throughput drug screening
- Drug-receptor interactions
- Proteins (and enzymes) and nucleic acids as drug targets
- Metals in medicine
- DNA-Drug interactions
- Drug metabolism and prodrugs and drug delivery
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Learning Outcomes |
On successful completion of this course, students should be able to:
- Demonstrate knowledge of drug discovery, design and development
- Understand drug-biomolecule interactions where appropriate
- Gain appropriate knowledge of drug metabolism and drug delivery
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Pre-requisites |
Pass in CHEM1003 or CHEM2402 or CHEM3405
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Offer in academic year
2011 - 2012
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2nd sem
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Availability in 2012 - 2013
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Y
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| Examination |
May
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| Teaching Hours |
24 lectures, 12 tutorials
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Assessment Method |
One 3-hour written examination (75% weighting); Continuous assessment of practical (25% weighting)
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Quota |
9999
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Textbooks |
- An Introduction to Medicinal Chemistry (3/e), G.L. Patrick, Oxford University Press, 2005
- Medicinal Chemistry- An Introduction, G. Thomas, John Wiley, 2000
- D. Wang, S.J. Lippard (2004) Nat. Rev. Drug Dis., Cellular processing of platinum anticancer drugs, 4, 307-320
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References |
NIL
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Course Website |
NIL
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Remarks |
NIL
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Status |
You had submitted at Feb 10, 2011
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Comment (For Department
Reference Only) |
This coruse is also offered to rpg students, but the course code for rpg students is CHEM6113.
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Last updated by CHEM at Feb 10, 2011
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