Curriculum Vitae of Professor Dan Yang
B.Sc. Fudan; M.A. Columbia; Ph.D. Princeton.

 

 

 

 

            Date of Birth: October 20, 1965
Place of Birth: Zigong, Sichuan, P. R. China 
Last Updated in April 2007  
 
                     
  Department of Chemistry
The University of Hong Kong
Pokfulam Road, Hong Kong
      

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(852)-2859-2159
(852)-2859-2159
yangdan@hku.hk
 		 
                     
       
                     
                     
 

Education

 
             
1981 - 1985
 B.S. in Chemistry, Fudan University, P. R. China.
1986 - 1988
 M.A., Columbia University (with Professor Ronald Breslow), research on the design and synthesis of artificial transaminases.
1988 - 1991


 Ph.D., Princeton University (with Professor Daniel Kahne), research on the stereoselective synthesis of calicheamicin core trisaccharide.
1991 - 1993



 Cancer Research Institute Postdoctoral Research Fellow, Harvard University (with Professor Stuart L. Schreiber), research on the cellular receptor of immunosuppressant FK506 and on the design and synthesis of new immunosuppressants.
   
[ Top ]
               
Academic Appointment
               
 
09/1993¡V08/1999
 Assistant Professor of Chemistry (tenured on July 1, 1996),
The University of Hong Kong.
    
09/1999¡V06/2000
 Associate Professor of Chemistry, The University of Hong Kong.
07/2000¡V12/2004
 Professor of Chemistry, The University of Hong Kong.
01/2005¡Vpresent
 Chair Professor of Chemistry, The University of Hong Kong.
04/2007¡Vpresent
 Morningside Professor in Chemical Biology, The University of Hong Kong.
   
   
               
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Professional Activities
 
 
  • Member of Editorial Advisory Board of Accounts of Chemical Research (2007 -)
  • Member of Advisory Editorial Board for Beilstein Journal of Organic Chemistry (2005 -)
  • Member of Faculty of 1000 (Biology Reports Ltd.), in the Macromolecular Chemistry Section under Chemical Biology Faculty (2004 -)
  • Guest Editor for Tetrahedron Symposium-in-Print on Recent Advances in Oxidation Chemistry (2006)
  • Member of the American Chemical Society
  • Visiting Professor, Lanzhou University (01/2000 - 12/2004)
  • Visiting Professor, Shanghai Institute of Materia Medica (07/2001 - Present)
  • Professor of Chemistry, Fudan University (06/2001 - 05/2004)
  • Special Chair Professor, Fudan University (05/2004 - 02/2006)
  • Chang-Jiang Special Professor, Fudan University (03/2006 - Present)
    
 
[ Top ]
   
Research Interests
 
  Asymmetric catalysis and total synthesis, design and synthesis of novel foldamers, and chemical biology of natural products.    
 
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Awards
 
 
  • Eli Lilly Scientific Excellence Award in China, 2006
  • Ten Outstanding Young Persons Award, Junior Chamber International Hong Kong, October 2004
  • Outstanding Researcher Award, The University of Hong Kong, August 2003
  • National Outstanding Young Scholar Award, The Natural Science Foundation of China, 2003 - 2005
  • Bristol-Myers Squibb Foundation¡¦s Unrestricted Grant Award in Synthetic Organic Chemistry, 2001 - 2004
  • Croucher Senior Research Fellowship Award, 2001-2002
  • Mr. and Mrs. Sun Chan Memorial Award in Organic Chemistry (shared with Professor
    Gregory C. Fu at MIT), January 2000
  • Outstanding Young Researcher Award, The University of Hong Kong, December 1999
  • Postdoctoral Fellowship Award, Cancer Research Institute (New York), September 1991 - August 1993
  • Ph.D. Fellowship for the Chemistry Graduate Program, Ministry of Education, P. R. China, September 1986 - August 1987
  • Graduate with the highest honor, Fudan University, July 1985
  • Excellent Student Award, Fudan University, September 1981 - July 1985
    
 
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Special Lectureships
 
 
  • Novartis Chemistry Lecturer, Novartis Institute for Biomedical Research (Sept. 2007; Basel, Switzerland; Vienna, Austria)
  • Abbott Process Chemistry Lecturer, University of Wisconsin (May 2006; Madison, USA)
  • LEO Pharma Lecturer, Technical University of Denmark (May 2006; Copenhagen, Denmark)
  • Rosalind Franklin International Lecturer, Imperial College (Mar. 2004; London, U.K.)
  • Aulin-Erdtman Lecturer, Royal Institute of Technology (Dec. 2002; Stockholm, Sweden)
   
 
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Invited lectures at Conferences and Institutions
   
  1. Invited lecture at the symposium Trend in Organic Chemistry ¡V Metal Mediated Reactions (Dec. 2007; Goteborg, Sweden)
  2. Invited lecture at the Symposium on Chemical Sensing and Molecular Imaging (Mar. 2007; Hong Kong, China)
  3. Invited lecture at the 1st International Conference of Cutting-Edge Organic Chemistry in Asia (Oct. 2006; Okinawa, Japan)
  4. Invited lecture at Chiral China 2006 (Aug. 2006; Chengdu, China)
  5. Invited lecture at ICOB-5 & ISCNP-25 IUPAC International Conference on Biodiversity and Natural Products Chemistry (Jul. 2006; Kyoto, Japan)
  6. Invited lecture at IUPAC Pre-symposium on Bioorganic Chemistry and Chemical Biology Chemistry (Jul. 2006; Nagoya, Japan)
  7. Invited lecture at the China-Germany Joint Workshop on Organocatalysis and Certain Aspects of Green Chemistry (Apr. 2006; Hangzhou, China)
  8. Invited lecture at the Congress of PACIFICHEM 2005 symposium entitled "Chemistry and Biology of NO and Reactive Oxygen Species" (Dec. 2005; Honolulu, USA)
  9. Invited lecture at the Congress of PACIFICHEM 2005 symposium entitled "Total Synthesis of Natural Products" (Dec. 2005; Honolulu, USA)
  10. Invited lecture at the 4th Workshop on Frontier Applied Chemistry Research: "Chronicling More Than Three Decades. Inorganic Chemistry in Biomedical and Materials Sciences" (Nov. 2005; Hong Kong)
  11. Invited lecture at the XIth NOST Symposium (Oct. 2005; Goa, India)
  12. Invited lecture at the 4th National Symposium on Chemical Biology (Oct. 2005; Wuhan, China)
  13. Invited lecture at the CCS 4th National Organic Chemistry Conference (Aug. 2005; Kunming, China)
  14. Invited lecture at Princeton University (Jul. 2005; USA)
  15. Invited lecture at the Gordon Research Conference on Natural Products Chemistry (Jul. 2005; New Hampshire, USA)
  16. Invited lecture at the Modern Synthetic Methods & Chiral USA 2005 (Jul. 2005, Princeton, USA)
  17. Invited lecture at Fudan University (Jun. 2005; Shanghai, China)
  18. Invited lecture at Shanghai Institute of Organic Chemistry (Jun. 2005; Shanghai, China)
  19. Invited lecture at Shanghai Institute of Materia Medica (Jun. 2005; Shanghai, China)
  20. Plenary lecture at the 39th National Organic Chemistry Symposium (Jun. 2005; Utah, USA)
  21. Invited lecture at the 2nd Fukuoka Symposium on "New-Generation Catalysts for New-Generation Synthesis" (Jan. 2005; Fukuoka, Japan)
  22. Invited lecture at the International Conference on Rare Earths 2004 (Nov. 2004; Nara, Japan)
  23. Invited lecture at California Institute of Technology (Oct. 2004; USA)
  24. Plenary lecture at the 3rd National Organic Chemistry Symposium 2004 (Aug. 2004; Lanzhou, China)
  25. Invited lecture at the IUPAC 15th International Conference on Organic Synthesis (Aug. 2004; Nagoya, Japan)
  26. Invited lecture at the Gordon Research Conference on Heterocyclic Compounds (Jul. 2004; Rhode Island, USA)
  27. Plenary lecture at the 9th International Symposium on Organic Free Radicals (Jun. 2004; Corsica, France)
  28. Invited lecture at University of Bristol (Mar. 2004; Bristol, U.K.)
  29. Invited lecture at Cardiff University (Mar. 2004; Cardiff, U.K.)
  30. Invited lecture at University of Southampton (Mar. 2004; Southampton, U.K.)
  31. Plenary lecture at the Ta-shue Chou Memorial Symposium (Feb. 2003; Taiwan)
  32. Invited lecture at Hong Kong Baptist University (Dec. 2002; Hong Kong)
  33. Plenary lecture at the CMDS Symposium 2002 (Frontiers in Asymmetric Synthesis) (Oct. 2002; KAIST, Taejon, Korea)
  34. Invited lecture at the 2nd National Symposium on Chemical Biology (Oct. 2002; Beijing, China)
  35. Invited lecture at the 1st Sino-Japanese Symposium on Organic Chemistry for Young Scientists (Sept. 2002; Shanghai, China)
  36. Invited lecture at Hong Kong University of Science and Technology (Aug. 2002; Hong Kong)
  37. Invited lecture in the Future of Organic Chemistry Lecture Series at Stanford University (Aug. 2002; USA)
  38. Invited lecture at the Gordon Research Conference on Organic Reactions and Processes (Jul. 2002; Rhode Island, USA)
  39. Invited lecture at the Gordon Research Conference on Stereochemistry (Jun. 2002; Rhode Island, USA)
  40. Invited lecture at the International Symposium on Design of Electron Transfer Systems for Green Organic Synthesis and New Intelligent Materials (Jun. 2002; Okayama, Japan)
  41. Research Seminars at The University of Tokyo, Keio University, and Gakushuin University (June 2002)
  42. Invited lecture at the 4th Annual Bristol-Myers Squibb Chemistry Award Symposium (Apr, 2002; Wallingford, USA)
  43. Invited lecture at UCLA for the Symposium entitled "Fifty Years of Cram's Rule: The Golden Age of Stereochemistry" (Mar. 2002; Los Angeles, USA)
  44. Invited lecture at the 2nd Singapore International Chemical Conference - Frontiers in Chemical Design and Synthesis (Dec. 2001, Singapore)
  45. Invited lecture at the 23rd Princeton ACS Fall Organic Chemistry Symposium (Sept. 2001; Princeton, USA)
  46. Research seminars at The University of Chicago and Northwestern University (Sept. 2001)
  47. Invited lecture at the 18th International Congress of Heterocyclic Chemistry (Jul. 2001; Yokohama, Japan)
  48. Research Seminar at Yale University (Mar. 2001)
  49. Invited lecture at the 2nd International Conference on Oxidation in Organic Chemistry - Potential Industrial Applications (Sept. 2000; York, UK)
  50. Plenary lecture at the 6th International Symposium for Chinese Organic Chemists (Jul. 2000; Shanghai, China)
  51. Invited lecture in the Lectures in the Chemical Sciences Series at Harvard University (Nov. 1999; USA)
  52. Research seminars at UC-Berkeley and Stanford (Nov. 1999)
  53. Plenary lecture at the 8th Chinese Chemical Society National Symposium on Organic Synthesis (Nov. 1999; Xiamen, China)
  54. Invited lecture at the 8th Asian Chemical Congress (Nov. 1999; Taipei, Taiwan)
  55. Research seminars at UCLA and Pittsburgh (Jun. 1999)
  56. Research seminars at UCLA, Columbia, and Princeton (Feb. 1999)
  57. Invited lecture at the Fifth International Symposium for Chinese Organic Chemists (Aug. 1998)
  58. Research seminars at Wisconsin-Madison, UCLA, UC-Irvine, and Scripps Research Institute (Jan. 1998)
  59. Invited lecture at the Second Conference for Worldwide Chinese Young Chemists (Dec. 1997)
  60. Invited lecture at the Asymmetric and Biomimetic Oxidation Workshop (Dec. 1996)
  61. Invited lecture at the Fifth Eurasia Conference on Chemical Sciences (Dec. 1996)
  62. A short talk at the Gordon Research Conference on Bioorganic Chemistry (Jun. 1995)
   
[ Top ]
                   
Publications (* for the corresponding author)  
                   
 
  1. D. Kahne*, D. Yang, J. J. Lim, R. Miller, E. Paguaga. The Use of Alkoxy Substituted Anomeric Radicals for the Construction of b-Glycosides. J. Am. Chem. Soc. 1988, 110, 8716¡V8717.
  2. D. Kahne*, D. Yang, M. D. Lee. Preparation of the 4-Ethylamino Sugar of Calicheamicin: Assignment of Absolute Configuration. Tetrahedron Lett. 1990, 31, 21¡V22.
  3. R. Breslow*, J. W. Canary, M. Varney, S. T. Waddell, D. Yang. Artificial Transaminases Linking Pyridoxamine to Binding Cavities: Controlling the Geometry. J. Am. Chem. Soc. 1990, 112, 5212¡V5219.
  4. D. Yang, S. H. Kim, D. Kahne*. Construction of Glycosidic N¡VO Linkages in Oligosaccharides. J. Am. Chem. Soc. 1991, 113, 4715¡V4716.
  5. S. Walker, D. Yang, D. Kahne*, D. Gange. Conformational Analysis of the N¡VO Bond in the Calicheamicin Oligosaccharides. J. Am. Chem. Soc. 1991, 113, 4716¡V4717.
  6. D. Yang, M. K. Rosen, S. L. Schreiber*. The Composite FKBP-FK506 Surface That Contacts Calcineurin. J. Am. Chem. Soc. 1993, 115, 819¡V820.
  7. M. K. Rosen, D. Yang, P. K. Martin, S. L. Schreiber*. Activation of an Inactive Immunophilin by Mutagenesis. J. Am. Chem. Soc. 1993, 115, 821¡V822.
  8. S.-H. Kim, D. Augeri, D. Yang, D. Kahne*. Concise Synthesis of the Calicheamicin Oligosaccharide Using the Sulfoxide Glycosylation Method. J. Am. Chem. Soc. 1994, 116, 1766¡V1775.
  9. D. Yang*, M.-K. Wong, Y.-C. Yip. Epoxidation of Olefins Using Methyl(trifluoromethyl)dioxirane Generated in situ. J. Org. Chem. 1995, 60, 3887¡V3889.
  10. D. Yang*, Y.-C. Yip, M.-W. Tang, M.-K. Wong, J.-H. Zheng, K.-K. Cheung. A C2 Symmetric Chiral Ketone for Catalytic Asymmetric Epoxidation of Unfunctionalized Olefins. J. Am. Chem. Soc. 1996, 118, 491¡V492. Condensation and commentary: Van Horn, J. D.; Richmond, T. G. Chemtracts¡VInorganic Chemistry 1998, 10, 89¡V94.
  11. D. Yang*, F.-F. Ng, Z.-J. Li, Y.-D. Wu, K. W.-K. Chan, D.-P. Wang. An Unusual Turn Structure in Peptides Containing a-Aminoxy Acids. J. Am. Chem. Soc. 1996, 118, 9794¡V9795.
  12. D. Yang*, X.-C. Wang, M.-K. Wong, Y.-C. Yip, M.-W. Tang. Highly Enantioselective Epoxidation of Trans-Stilbenes Catalyzed by Chiral Ketones. J. Am. Chem. Soc. 1996, 118, 11311¡V11312.
    Condensation and commentary: Bergbreiter, D. E. Chemtracts¡VOrganic Chemistry 1997, 10, 661¡V664.
    Van Horn, J. D.; Richmond, T. G. Chemtracts¡VInorganic Chemistry 1998, 10, 89¡V94.
  13. D. Yang*, M.-K. Wong, K.-K. Cheung, E. W. C. Chan, Y. Xie. Studies on Triepoxide Analogs of Triptolide. Tetrahedron Lett. 1997, 38, 6865¡V6868.
  14. D. Yang*, Y.-C. Yip, X.-C. Wang. Oxidative Cleavage of Aryl Oxazolines Using Methyl(trifluoromethyl)dioxirane Generated in situ. Tetrahedron Lett. 1997, 38, 7083¡V7086.
  15. D. Yang*, M.-K. Wong, Y.-C. Yip, X.-C. Wang, M.-W. Tang, J.-H. Zheng, K.-K. Cheung. Design and Synthesis of Chiral Ketones for Catalytic Asymmetric Epoxidation of Unfunctionalized Olefins. J. Am. Chem. Soc. 1998, 120, 5943¡V5952.
  16. D. Yang*, M.-K. Wong, X.-C. Wang, Y.-C. Tang. Regioselective Intramolecular Oxidation of Unactivated C¡VH Bonds by Dioxiranes Generated in situ. J. Am. Chem. Soc. 1998, 120, 6611¡V6612.
  17. D. Yang*, Y.-C. Yip, J. Chen, K.-K. Cheung. Significant Effects of Non-Conjugated Remote Substituents in Catalytic Asymmetric Epoxidation. J. Am. Chem. Soc. 1998, 120, 7659¡V7660.
  18. D. Yang*, X.-Y. Ye, M. Xu, K.-W. Pang, N. Zou, R. M. Letcher. A Concise Total Synthesis of Triptolide. J. Org. Chem. 1998, 63, 6446¡V6447.
  19. D. Yang*, Y.-C. Yip, G.-S. Jiao, M.-K. Wong. Design of Efficient Ketone Catalysts for Epoxidation by Using the Field Effect. J. Org. Chem. 1998, 63, 8952¡V8956.
  20. D. Yang*, Y.-C. Yip, M.-W. Tang, M.-K. Wong, K.-K. Cheung. Novel Cyclic Ketones for Catalytic Oxidation Reactions. J. Org. Chem. 1998, 63, 9888¡V9894.
  21. D. Yang*, J. Qu, B. Li, F.-F. Ng, X.-C. Wang, K.-K. Cheung, D.-P. Wang, Y.-D. Wu*. Novel Turns and Helices in Peptides of Chiral a-Aminoxy Acids. J. Am. Chem. Soc. 1999, 121, 589¡V590.
  22. D. Yang*, G.-S. Jiao, Y.-C. Yip, M.-K. Wong. Diastereoselective Epoxidation of Cyclohexene Derivatives by Dioxiranes Generated in situ. Importance of Steric and Field Effects. J. Org. Chem. 1999, 64, 1635¡V1639.
  23. D. Yang*, X.-Y. Ye, S. Gu, M. Xu. Lanthanide Triflates Catalyze Mn(III)-Based Oxidative Radical Cyclization Reactions. Enantioselective Synthesis of (¡V)-Triptolide, (¡V)-Triptonide, and (+)-Triptophenolide. J. Am. Chem. Soc. 1999, 121, 5579¡V5580.
  24. K. K. Tong, D. Yang, E. Y. T. Chan, P. K. Y. Chiu, K. S. Yau, C. S. Lau*. Down Regulation of Lymphocyte Activity and Human Synovial Fibroblast Growth in Rheumatoid Arthritis by Triptolide. Drug Dev. Res. 1999, 47, 144-53.
  25. Y.-D. Wu*, D.-P. Wang, K. W. K. Chan, D. Yang*. Theoretical Study of Peptides Formed by Aminoxy Acids. J. Am. Chem. Soc. 1999, 121, 11189-11196.
  26. D. Yang*, Y.-C. Tang, J. Chen, X.-C. Wang, M. D. Bartberger, K. N. Houk, L. Olson. Ketone-Catalyzed Decomposition of Peroxynitrite via Dioxirane Intermediates. J. Am. Chem. Soc. 1999, 121, 11976-11983.
  27. D. Yang*, X.-Y. Ye, M. Xu, K.-W. Pang, K.-K. Cheung. Investigation of Mn(III)-Based Oxidative Free Radical Cyclization Reactions toward the Synthesis of Triptolide: The Effects of Lanthanide Triflates and Substituents on Stereoselectivity. J. Am. Chem. Soc. 2000, 122, 1658-1663.
  28. D. Yang*, X.-Y. Ye, M. Xu. Enantioselective Total Synthesis of (-)-Triptolide, (-)-Triptonide, and (+)-Triptophenolide, and (+)-Triptoquinonide. J. Org. Chem. 2000, 65, 2208-2217.
  29. D. Yang*, C. Zhang, X.-C. Wang. A Novel Epoxidation Reaction of Olefins Using a Combination of Chloramine-M, Benzaldehyde, and Benzyltriethylammonium Chloride. J. Am. Chem. Soc. 2000, 122, 4039-4043.
  30. D. Yang*, M.-K. Wong, Z. Yan. Regioselective Intramolecular Oxidation of Phenols and Anisols by Dioxiranes Generated in situ. J. Org. Chem. 2000, 65, 4179-4184.
  31. D. Yang*, G.-S. Jiao. Highly b-Selective Epoxidation of D5-Unsaturated Steroids Catalysed by Ketones. Chem. Eur. J. 2000, 6, 3517-3521.
  32. D. Yang*, M. Xu, M.-Y. Bian. Chiral Auxiliaries for Asymmetric Radical Cyclization Reactions: Application to the Enantioselective Synthesis of (+)-Triptocallol. Org. Lett. 2001, 3, 111-114.
  33. D. Yang*, Y.-C. Yip, G.-S. Jiao, M.-K. Wong. In Situ Catalytic Epoxidation of Olefins with Tetrahydrothiopyran-4-one and Oxone: 2-Methyl-2,3-Diphenyloxirane. Org. Syn. 2001, 78, 225-233.
  34. M.-K. Wong*, C.-W. Yu, W.-H. Yuen, D. Yang*. Synthesis of a-Keto Esters and Amides via Oxidative Cleavage of Cyanoketophosphoranes by Dimethyldioxirane. J. Org. Chem. 2001, 66, 3606-3609.
  35. D. Yang*, G.-S. Jiao, Y.-C. Yip, T.-H. Lai, M.-K. Wong. Kinetic Resolution of Acyclic Secondary Allylic Silyl Ethers Catalyzed by Chiral Ketones. J. Org. Chem. 2001, 66, 4619-4624.
  36. D. Yang*, M. Xu. First Enantioselective Syntheses of (+) and (-)-Wilforonide by Using Chiral Auxiliaries Derived from the Same Chiral Source. Org. Lett. 2001, 3, 1785-1788.
  37. D. Yang*, C. Zhang. Ruthenium-Catalyzed Oxidative Cleavage of Olefins to Aldehydes. J. Org. Chem. 2001, 66, 4814-4818.
  38. M.-K. Wong*, L.-M. Ho, Y.-S. Zheng, C.-Y. Ho, D. Yang*. Asymmetric Epoxidation of Olefins Catalyzed by Chiral Iminium Salts Generated in situ from Amines and Aldehydes. Org. Lett. 2001, 3, 2587-2590.
  39. D. Yang*, S. Gu, Y.-L. Yan, N.-Y. Zhu, K.-K. Cheung. Highly Enantioselective Atom-transfer Radical Cyclization Reactions Catalyzed by Lewis Acids. J. Am. Chem. Soc. 2001, 123, 8612-8613.
  40. X.-H. Jiang, B. C.-Y. Wong*, M. C.-M. Lin, G.-H. Zhu, H.-F. Kung, S.-H. Jiang, D. Yang, S.-K. Lam. Functional p53 is required for Triptolide-induced apoptosis and AP-1 and Nuclear Factor-kB activation in Gastric cancer cells. Oncogene, 2001, 20, 8009-8018.
  41. D. Yang*, B. Li, F.-F. Ng, Y.-L. Yan, J. Qu, Y.-D. Wu. Synthesis and Characterization of Chiral N-O Turns Induced by a-Aminoxy Acids. J. Org. Chem. 2001, 66, 7303-7312.
  42. D. Yang*, Q. Gao, O.-Y. Lee. Lewis Acid-Promoted Phenylseleno Group Transfer Tandem Radical Cyclization Reactions. Org. Lett. 2002, 4, 1239-1241.
  43. D. Yang*, S. Gu, H.-W. Zhao, Y.-L. Yan, N.-Y. Zhu. Atom-Transfer Tandem Radical Cyclization Reactions Promoted by Lewis Acids. Angew. Chem. Int. Ed. 2002, 41, 3014-3017.
  44. D. Yang*, Y.-H. Zhang, N. Y. Zhu. £]2,2-Aminoxy Acids: A New Building Block for Turns and Helices. J. Am. Chem. Soc. 2002, 124, 9966-9967.
  45. D. Yang*, Q. Gao, C.-S. Lee, K.-K. Chueng. A Novel Intramolecular Cyclopropanation Reaction of Unsaturated b-Keto Esters. Org. Lett. 2002, 4, 3271-3274.
  46. D. Yang*, J. Qu, W. Li, Y.-H. Zhang, D.-P. Wang, Y.-D. Wu*. A Cyclic Hexapeptide of D,L-a-Aminoxy Acids as a Selective Receptor for Chloride Ion. J. Am. Chem. Soc. 2002, 124, 12410-12411.
  47. D. Yang*, Y.-L. Yan, B. Lui. Mild a-Halogenation Reactions of 1,3-Dicarbonyl Compounds Catalyzed by Lewis Acids. J. Org. Chem. 2002, 67, 7429-7431.
  48. M.-K. Wong, N.-W. Chung, L. He, D. Yang*. Substituent Effects on Regioselective Intramolecular Oxidation of Unactivated C-H Bonds: Stereoselective Synthesis of Substituted Tetrahydropyrans. J. Am. Chem. Soc. 2003, 125, 158-162.
  49. M.-K. Wong, N.-W. Chung, L. He, X.-C. Wang, Z. Yan, Y.-C. Tang, D. Yang*. Investigation on the Regioselectivities of Intramolecular Oxidation of Unactivated C-H Bonds by Dioxiranes Generated in Situ. J. Org. Chem. 2003, 68, 6321-6328.
  50. D. Yang*, J.-H. Li, Q. Gao, Y.-L. Yan. Lanthanide Triflate-Promoted Palladium-Catalyzed Cyclization of Alkenyl b¡VKeto Esters and Amides. Org. Lett. 2003, 5, 2869-2871.
  51. D. Yang*, W. Li, J. Qu, S.-W. Luo, Y.-D. Wu*. A New Strategy to Induce g-Turns: Peptides Composed of Alternating a-Aminoxy Acids and a-Amino Acids. J. Am. Chem. Soc. 2003, 125, 13018-13019.
  52. D. Yang*, Y.-L. Yan, K.-L. Law, N.-Y. Zhu. Lewis Acid-Catalyzed Atom Transfer Radical Cyclization of Unsaturated b-Keto Amides. Tetrahedron 2003, 59, 10465-10475. (Invited article to a special edition entitled ¡§Recent Advances in Rare Earth Chemistry¡¨)
  53. D. Yang*, B.-F. Zheng, S. Gu, P. W. H. Chan, N.-Y. Zhu. Lewis Acid-Catalyzed Asymmetric Atom Transfer Radical Cyclization Reactions of a-Bromo Oxazolidinones. Tetrahedron: Asymmetry 2003, 14, 2927-2937. (Invited article to a special edition entitled ¡§Stereoselective Radical Reactions¡¨)
  54. D. Yang*, M. Yang, N.-Y. Zhu. Chiral Lewis Acid-Catalyzed Enantioselective Intramolecular Carbonyl Ene Reactions of Unsaturated £\-Keto Esters. Org. Lett. 2003, 5, 3749-3752.
  55. D. Yang*, J. Qu, D.-P. Wang, Y. Ren, Y.-D. Wu*. A Reverse-Turn Structure Induced by Two Consecutive D,L-a-Aminoxy Acids. J. Am. Chem. Soc. 2003, 125, 14452-14457.
  56. D. Yang*, F. Chen, Z.-M. Dong, D.-W. Zhang. Ruthenium-Catalyzed Oxidative Cleavage of Alkynes to Carboxylic Acids. J. Org. Chem. 2004, 69, 2221-2223.
  57. D. Yang*, Y.-C. Chen, N.-Y. Zhu. Sterically Bulky Thioureas as Air and Moisture Stable Ligands for Pd-Catalyzed Heck Reactions of Aryl Halides. Org. Lett. 2004, 6, 1577-1580.
  58. D. Yang*, Y.-H. Zhang, B. Li, D.-W. Zhang, J. C.-Y. Chan, N.-Y. Zhu, S.-W. Luo, Y.-D. Wu*. Effect of Side Chains on Turns and Helices in Peptides of b3-Aminoxy Acids. J. Am. Chem. Soc. 2004, 126, 6956-6966.
  59. D. Yang. Ketone-Catalyzed Asymmetric Epoxidation Reactions. Acc. Chem. Res. 2004, 37, 497-505. (Invited article to a special issue entitled ¡§Enantioselective Organocatalysis¡¨)
  60. D. Yang*, Y.-H. Zhang, B. Li, D.-W. Zhang. The Synthesis of Chiral b3-Aminoxy Peptides. J. Org. Chem. 2004, 69, 7577-7581.
  61. R.Y. Kao*, W.H.W. Tsui, T.S.W. Lee, J.A. Tanner, R.M. Watt, J.D. Huang, L.H. Hu, G.H. Chen, Z.W. Chen, L.Q. Zhang, T. He, K.H. Chan, H. Tse, A.P.C. To, L.W.Y. Ng, B.C.W. Wong, H.W. Tsoi, D. Yang, D.D. Ho, K.Y. Yuen. Identification of Novel Small Molecule Inhibitors of Severe Acute Respiratory Syndrome Associated Coronavirus by Chemical Genetics. Chem. Biol. 2004, 11, 1293-1299.
  62. D. Yang*, D.-W. Zhang, Y. Hao, Y.-D. Wu, S.-W. Luo, N.-Y. Zhu. b2, 3-Cyclic Aminoxy Acids: Rigid and Ring Size-Independent Building Blocks of Foldamers. Angew. Chem., Int. Ed. 2004, 43, 6719-6722.
  63. D. Yang,* Q. Gao, B.-F. Zheng, N.-Y. Zhu. Et2AlCl-Promoted Asymmetric Phenylseleno Group Transfer Radical Cyclization Reactions of Unsaturated b-Hydroxy Esters. J. Org. Chem. 2004, 69, 8821-8828.
  64. F. Chen, N.-Y. Zhu, D. Yang*. g4-Aminoxy Peptides as New Peptidomimetic Foldamers. J. Am. Chem. Soc. 2004, 126, 15980-15981.
  65. C.-Y. Ho, Y.-C. Chen, M.-K. Wong, D. Yang*. Epoxidation of Olefins Catalyzed by Chiral Fluorinated Secondary Amines. J. Org. Chem. 2005, 70, 898-906.
  66. D. Yang*, X. Li, Y. Sha, Y.D. Wu*. A Cyclic Hexapeptide Comprising Alternating a-Aminoxy Acids and a-Amino Acids is a Selective Chloride Anion Receptor. Chem. Eur. J. 2005, 11, 3005-3009
  67. Q. Gao, B.F. Zheng, J.H. Li, D. Yang*. Ni(II)-Catalyzed Conia-Ene Reaction of 1,3-Dicarbonyl Compounds with Alkynes. Org. Lett. 2005, 7, 2185-2188.
  68. D. Yang*, X. Li, Y.F. Fan, D.W. Zhang. An Enantioselective Carboxylate Receptor Derived from a-Aminoxy Acids Functions as a Chiral Shift Reagent. J. Am. Chem. Soc. 2005, 127, 7996-7997.
  69. Li, J.H.*; Zhu, Q.M.; Liang, Y.; Yang, D. Efficient and Reusable PdCl2(MeCN)2/CuCl2/PEG-400 System for Cyclization of Alkenyl b-Keto Esters and Amides. J. Org. Chem. 2005, 70, 5347-5349.
  70. K.T. Yip, J.H. Li, O.Y. Lee, D. Yang*. Aerobic Oxidative Cyclization Under Pd(II) Catalysis: A Regioselective Approach to Heterocycles. Org. Lett. 2005, 7, 5717-5719.
  71. D.S.S. Kumar, C.S. Lau*, J.M.F. Wan, D. Yang, K.D. Hyde. Immunomodulatory compounds from Pestalotiopsis leucothes, an endophytic fungus from Tripterygium wilfordii. Life Sciences 2005, 78, 147-156.
  72. D. Yang*, B.F. Zheng, Q. Gao, S. Gu, N.Y. Zhu. Enantioselective PhSe Group Transfer Tandem Radical Cyclization Reactions Catalyzed by a Chiral Lewis Acid. Angew. Chem., Int. Ed. 2006, 45, 255-258.
  73. W. Chen, R. Li, B. Han, B.J. Li, Y.C. Chen*, Y. Wu, L.S. Ding, D. Yang. The Design and Synthesis of Bis(thiourea) Ligands and Their Application in Pd-Catalyzed Heck and Suzuki Reactions Under Aerobic Conditions. Eur. J. Org. Chem. 2006, 1177-1184.
  74. X.G. Guan, D.L. Phillips*, D. Yang*. A Density Functional Theory Study of the 5-Exo Cyclization Reactions of a-Substituted 6,6-Diphenyl-5-hexenyl Radicals. J. Org. Chem. 2006, 71, 1984-1988.
  75. K.T. Yip, M. Yang, K.L. Law, N.Y. Zhu, D. Yang*. Pd(II)-Catalyzed Enantioselective Oxidative Tandem Cyclization Reactions. Synthesis of Indolines through C-N and C-C Bond Formation. J. Am. Chem. Soc. 2006, 128, 3130-3131.
  76. D. Yang*, H.-L. Wang, Z.-N. Sun, N.-W. Chung, J.-G. Shen. A Highly Selective Fluorescent Probe for the Detection and Imaging of Peroxynitrite in Living Cells. J. Am. Chem. Soc. 2006, 128, 6004-6005.
  77. X. Li, D. Yang*. Peptides of Aminoxy Acids as Foldamers. Chem. Commun. 2006, 3367-3379. (Invited Feature Article)
  78. M. Yang, K.-T. Yip, J.-H. Pan, Y.-C. Chen, N.-Y. Zhu, D. Yang*. A Sterically Bulky Cyclic Thiourea as an Efficient Ligand for Palladium-Catalyzed Aerobic Oxidation of Alcohols. Synlett 2006, 3057-3060. (Invited article for a special issue dedicated to Professor Richard Heck)
  79. D. Yang*, Y.-L. Yan, B.-F. Zheng, Q. Gao, N.-Y. Zhu. Copper(I)-Catalyzed Chlorine Atom Transfer Radical Cyclization Reactions of Unsaturated a-Chloro b-Keto Esters. Org. Lett. 2006, 8, 5757-5760.
  80. F. Chen, D. Yang*. Condensation of Amino Acids to Form Peptides in Aqueous Solution Induced by the Oxidation of Sulfur(IV): An Oxidative Model for Prebiotic Peptide Formation. Origins Life Evol. Biospheres, 2007, 37, 47-54.
   
 
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Book Chapters  
                   
 
  1. D. Yang*, F. Chen, D. W. Zhang, Y. D. Wu. Advances in Chemicobiology, Chapter 5.1 b-Peptide and Its Analogs (Review article, in Chinese), 275-316, Beijing, Chemical Industry Press, 2005.
    
 
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Patents  
                   
 
  1. D. Yang, J.-H. Zhang, M.-K. Wong, Y.-C. Yip, M.-W. Tang. Process for Catalytic Epoxidation of Olefinic Compounds, Novel Cyclic Ketone Catalysts Useful in Said Process. U.S. Patent 5,763,623, 1998.
  2. D. Yang, G.-S. Jiao. Method for Synthesizing 5b,6b-Epoxides of Steroids by a Highly b-Selective Epoxidation of D5-Unsaturated Steroids Catalysed by Ketones. U.S. Patent 6,841,665, 2005.
  3. D. Yang, G.-S. Jiao. Method for Synthesizing 5b,6b-Epoxides of Steroids by a Highly b-Selective Epoxidation of D5-Unsaturated Steroids Catalysed by Ketones. PCT patent application (No. PCT/CN03/00140) filed on Feb. 24, 2003.
  4. D. Yang, Y.-C. Chen. Thiourea Compositions and Uses Thereof. U.S. Provisional Patent Application (No. 60/556,570), filed on Mar. 26, 2004. U.S. Non-Provisional Patent Application (No. 11/089,197), filed on Mar. 24, 2005.
  5. D. Yang, Y.-C. Chen. Thiourea Compositions and Uses Thereof. PCT patent application (No. PCT/CN2005/000391) filed on Feb. 28, 2005.
  6. D. Yang, H.-L. Wang, Z.-N. Sun, J.-G. Shen. Reagents for Highly Specific Detection of Peroxynitrite. U.S. Non-Provisional Patent Application (No. 11/245,529), filed on Oct. 7, 2005.
  7. D. Yang, H.-L. Wang, Z.-N. Sun, J.-G. Shen. Reagents for Highly Specific Detection of Peroxynitrite. PCT Patent Application (No. PCT/CN2006/002177), filed on Aug. 25, 2006.
  8. X. Li, D. Yang. Synthetic Chloride Channels. U.S. Provisional Patent Application (No. 60/876,012), filed on Dec. 19, 2006.
    
 
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