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New Analytical Methods Development
Capillary
Electrophoresis (CE) and Related Separation Techniques: Capillary
Zone Electrophoresis (CZE), Micellar Electrokinetic Chromatography (MEKC),
Capillary Electrochromatography (CEC), Microchip-CE (Chip-CE), Micro-Total
Analytical System (£gTAS) and Microfluidic Lab-on-a-Chip System (£g-Lab-on-a-Chip).
Integrating
Separation with Detection & Sample Pretreatment: Detection
by Laser Induced Fluorescence detection (LIF), Electrochemical &
Electroluminescence detector (ECD/ELSD) for Chip-CE, £gTAS and £g-Lab-on-a-Chip;
Sample Pretreatment by Flow Injection Method (FID), Supercritical Fluid
Extraction (SFE), Micro-Solid Phase Extraction (£gSPE) and Molecular
Imprinted Polymer (MIP).
Chemical
and Biosensors: Piezoelectric Quartz Crystal (PQC) Chemical Sensor,
PQC Immunosensor, PQC DNA/PCR Biosensor, Electrochemical sensors based
on Micro-electrode (£gElectrode), Cathodic Stripping Analysis (CSV) &
Electroluminescence.
Chemometric
Methods: Assessing the quality of Traditional Chinese Medicine
and Pollution Source Apportionment by Chemical Analysis /Factor Analysis
(CA-FA).
Application to Food &
Drugs, Environmental and Biomedical Analysis
Food
& Pharmaceutical Analysis: 1) Determination of pesticides in
vegetables by CSV, 2) Geno-typing of Ginsengs from different botanical
origin by CE and chip-CE, 3) Assessing the quality of Traditional Chinese
Medicine by CA-FA.
Environmental
Analysis: 1) £gElectrode for insitu determination of pesticides
in frog¡¦s eggs, 2) Analysis of carbonyls, carboxylic acids and other
pollutants in air by CE and Microchip CE, 3) Analysis of pesticide residual
in drinking water by CE & MEKC, 4) Sensing VOCs and air particulate
matters by PQC.
Biomedical
Analysis: 1) CE and Chip-CE assay of free and albumin-bound bilirubin
in newborn babies, 2) PQC Biosensor based on antibody-antigen interaction
for assay of Salmonella, 3) PQC DNA Biosensor for assay of E. Coli after
PCR amplification, 4) Microchip CE with Tunable LIF Detection for assay
of Flavin derivatives, 5) Apportion sources of air particulates by CA-FA
for their health effect on human respiratory system.
New Electrochemical/Nanotechnologies
Nanotechnology:
Sizing, collection & characterization of industrial & biomedical
nano-particles, fabrication of electrophoretic coatings and developing
Quantum Dots for industrial & biomedical application.
Room
Temperature Molten Salt (RTMS) Technologies: Study and application
of 1-methyl-3-ethylimidazollium chloride/AlCl3 RTMS for secondary Lithium
Ion Battery and for Electrodeposition of alloys and superconductor precursors.
Lab-on-a-chip:
Technology for chemical analysis in the field and for bedside clinical
assay.
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